Publications

2020

  • Mighty J, Zhou J, Benito-Martin A, Sauma S, Hanna S, Onwumere O, Shi C, Muntzel M, Sauane M, Young M2, Molina H2, Cox D, Redenti S. Analysis of Adult Neural Retina Extracellular Vesicle Release, RNA Transport and Proteomic Cargo. Invest Ophthalmol Vis Sci. 2020 Feb 7;61(2):30. doi: 10.1167/iovs.61.2.30   PubMed PMID: 32084266
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2019

  • Mishra, S, Peña, JS, Redenti, S, Vazquez, M. A novel electro-chemotactic approach to impact the directional migration of transplantable retinal progenitor cells. Exp. Eye Res. 2019;185 :107688. doi: 10.1016/j.exer.2019.06.002. PubMed PMID:31185219 PubMed Central PMC6698415.
  • Gharbaran, R, Zhang, B, Valerio, L, Onwumere, O, Wong, M, Mighty, J et al.. Effects of vitamin D3 and its chemical analogs on the growth of Hodgkin's lymphoma, in vitro. BMC Res Notes. 2019;12 (1):216. doi: 10.1186/s13104-019-4241-0. PubMed PMID:30961641 PubMed Central PMC6454773.
  • Redenti, S, Marcovich, I, De Vita, T, Pérez, C, De Zorzi, R, Demitri, N et al.. A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. ChemMedChem. 2019;14 (3):310-314. doi: 10.1002/cmdc.201800778. PubMed PMID:30548443 .

2018

  • O’Connor, NA, Einbond, LS, Redenti, S, Sauane, M, Jitianu, A. A Self-degradable Curcumin Polymer with Anti-cancer Activity. J Appl Polym Sci. 2018;135 (47):. doi: 10.1002/app.46867. PubMed PMID:30555179 PubMed Central PMC6289511.
  • Persaud, L, Mighty, J, Zhong, X, Francis, A, Mendez, M, Muharam, H et al.. IL-24 Promotes Apoptosis through cAMP-Dependent PKA Pathways in Human Breast Cancer Cells. Int J Mol Sci. 2018;19 (11):. doi: 10.3390/ijms19113561. PubMed PMID:30424508 PubMed Central PMC6274865.
  • Zhou, J, Benito-Martin, A, Mighty, J, Chang, L, Ghoroghi, S, Wu, H et al.. Author Correction: Retinal progenitor cells release extracellular vesicles containing developmental transcription factors, microRNA and membrane proteins. Sci Rep. 2018;8 (1):15801. doi: 10.1038/s41598-018-32118-6. PubMed PMID:30348977 PubMed Central PMC6197281.
  • Einbond, LS, Soffritti, M, Esposti, DD, Wu, HA, Balick, M, Ma, H et al.. A transcriptomic analysis of black cohosh: Actein alters cholesterol biosynthesis pathways and synergizes with simvastatin. Food Chem. Toxicol. 2018;120 :356-366. doi: 10.1016/j.fct.2018.06.064. PubMed PMID:29969672 .
  • Pena, J, Dulger, N, Singh, T, Zhou, J, Majeska, R, Redenti, S et al.. Controlled microenvironments to evaluate chemotactic properties of cultured Müller glia. Exp. Eye Res. 2018;173 :129-137. doi: 10.1016/j.exer.2018.05.005. PubMed PMID:29753729 PubMed Central PMC6054825.
  • Zhou, J, Benito-Martin, A, Mighty, J, Chang, L, Ghoroghi, S, Wu, H et al.. Retinal progenitor cells release extracellular vesicles containing developmental transcription factors, microRNA and membrane proteins. Sci Rep. 2018;8 (1):2823. doi: 10.1038/s41598-018-20421-1. PubMed PMID:29434302 PubMed Central PMC5809580.
  • Einbond, LS, Manservisi, F, Wu, HA, Balick, M, Antonetti, V, Vornoli, A et al.. A transcriptomic analysis of turmeric: Curcumin represses the expression of cholesterol biosynthetic genes and synergizes with simvastatin. Pharmacol. Res. 2018;132 :176-187. doi: 10.1016/j.phrs.2018.01.023. PubMed PMID:29408497 .
  • Thakur, A, Mishra, S, Pena, J, Zhou, J, Redenti, S, Majeska, R et al.. Collective adhesion and displacement of retinal progenitor cells upon extracellular matrix substrates of transplantable biomaterials. J Tissue Eng. ;9 :2041731417751286. doi: 10.1177/2041731417751286. PubMed PMID:29344334 PubMed Central PMC5764132.

2017

  • Einbond, LS, Negrin, A, Kulakowski, DM, Wu, HA, Antonetti, V, Jalees, F et al.. Traditional preparations of kava (Piper methysticum) inhibit the growth of human colon cancer cells in vitro. Phytomedicine. 2017;24 :1-13. doi: 10.1016/j.phymed.2016.11.002. PubMed PMID:28160848 .
  • McCutcheon, S, Unachukwu, U, Thakur, A, Majeska, R, Redenti, S, Vazquez, M et al.. In vitro formation of neuroclusters in microfluidic devices and cell migration as a function of stromal-derived growth factor 1 gradients. Cell Adh Migr. 2017;11 (1):1-12. doi: 10.1080/19336918.2015.1131388. PubMed PMID:26744909 PubMed Central PMC5308225.

2016

  • Einbond, LS, Negrin, A, Kulakowski, DM, Wu, HA, Antonetti, V, Jalees, F et al.. Traditional preparations of kava (Piper methysticum) inhibit the growth of human colon cancer cells in vitro. Phytomedicine. 2017;24 :1-13. doi: 10.1016/j.phymed.2016.11.002. PubMed PMID:28160848 .
  • Unachukwu, UJ, Warren, A, Li, Z, Mishra, S, Zhou, J, Sauane, M et al.. Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina. Sci Rep. 2016;6 :22392. doi: 10.1038/srep22392. PubMed PMID:26935401PubMed Central PMC4776098.
  • Zhou, J, Ghoroghi, S, Benito-Martin, A, Wu, H, Unachukwu, UJ, Einbond, LS et al.. Characterization of Induced Pluripotent Stem Cell Microvesicle Genesis, Morphology and Pluripotent Content. Sci Rep. 2016;6 :19743. doi: 10.1038/srep19743. PubMed PMID:26797168 PubMed Central PMC4726265.
  • McCutcheon, S, Unachukwu, U, Thakur, A, Majeska, R, Redenti, S, Vazquez, M et al.. In vitro formation of neuroclusters in microfluidic devices and cell migration as a function of stromal-derived growth factor 1 gradients. Cell Adh Migr. 2017;11 (1):1-12. doi: 10.1080/19336918.2015.1131388. PubMed PMID:26744909 PubMed Central PMC5308225.
  • Einbond, LS, Wu, HA, Sandu, C, Ford, M, Mighty, J, Antonetti, V et al.. Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells. Fitoterapia. 2016;109 :146-54. doi: 10.1016/j.fitote.2015.12.005. PubMed PMID:26691294 .

2015

  • Einbond, LS, Wu, HA, Sandu, C, Ford, M, Mighty, J, Antonetti, V et al.. Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells. Fitoterapia. 2016;109 :146-54. doi: 10.1016/j.fitote.2015.12.005. PubMed PMID:26691294 .
  • Mishra, S, Thakur, A, Redenti, S, Vazquez, M. A model microfluidics-based system for the human and mouse retina. Biomed Microdevices. 2015;17 (6):107. doi: 10.1007/s10544-015-0002-6. PubMed PMID:26475458 .
  • Tucker, BA, Park, IH, Qi, SD, Klassen, HJ, Jiang, C, Yao, J et al.. Correction: Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice. PLoS ONE. 2015;10 (5):e0125947. doi: 10.1371/journal.pone.0125947. PubMed PMID:25950705 PubMed Central PMC4423907.
  • Yao, J, Ko, CW, Baranov, PY, Regatieri, CV, Redenti, S, Tucker, BA et al.. Enhanced differentiation and delivery of mouse retinal progenitor cells using a micropatterned biodegradable thin-film polycaprolactone scaffold. Tissue Eng Part A. 2015;21 (7-8):1247-60. doi: 10.1089/ten.TEA.2013.0720. PubMed PMID:25517296 PubMed Central PMC4394889.

2014

  • Federico, S, Ciancetta, A, Porta, N, Redenti, S, Pastorin, G, Cacciari, B et al.. Scaffold decoration at positions 5 and 8 of 1,2,4-triazolo[1,5-c]pyrimidines to explore the antagonist profiling on adenosine receptors: a preliminary structure-activity relationship study. J. Med. Chem. 2014;57 (14):6210-25. doi: 10.1021/jm500752h. PubMed PMID:24972108 .

2013

  • Unachukwu, UJ, Sauane, M, Vazquez, M, Redenti, S. Microfluidic generated EGF-gradients induce chemokinesis of transplantable retinal progenitor cells via the JAK/STAT and PI3kinase signaling pathways. PLoS ONE. 2013;8 (12):e83906. doi: 10.1371/journal.pone.0083906. PubMed PMID:24376770 PubMed Central PMC3871684.
  • Tandon, N, Cimetta, E, Taubman, A, Kupferstein, N, Madaan, U, Mighty, J et al.. Biomimetic electrical stimulation platform for neural differentiation of retinal progenitor cells. Conf Proc IEEE Eng Med Biol Soc. 2013;2013 :5666-9. doi: 10.1109/EMBC.2013.6610836. PubMed PMID:24111023 PubMed Central PMC4476523.
  • Saigal, R, Cimetta, E, Tandon, N, Zhou, J, Langer, R, Young, M et al.. Electrical stimulation via a biocompatible conductive polymer directs retinal progenitor cell differentiation. Conf Proc IEEE Eng Med Biol Soc. 2013;2013 :1627-31. doi: 10.1109/EMBC.2013.6609828. PubMed PMID:24110015 PubMed Central PMC4480863.
  • Do, W, Herrera, C, Mighty, J, Shumskaya, M, Redenti, SM, Sauane, M et al.. Sigma 1 Recz
  • Cai, S, Smith, ME, Redenti, SM, Wnek, GE, Young, MJ. Mouse retinal progenitor cell dynamics on electrospun poly (ϵ-caprolactone). J Biomater Sci Polym Ed. 2012;23 (11):1451-65. doi: 10.1163/092050611X584388. PubMed PMID:21781383 .

2011

  • Tucker, BA, Park, IH, Qi, SD, Klassen, HJ, Jiang, C, Yao, J et al.. Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. PLoS ONE. 2011;6 (4):e18992. doi: 10.1371/journal.pone.0018992. PubMed PMID:21559507 PubMed Central PMC3084746.
  • Sodha, S, Wall, K, Redenti, S, Klassen, H, Young, MJ, Tao, SL et al.. Microfabrication of a three-dimensional polycaprolactone thin-film scaffold for retinal progenitor cell encapsulation. J Biomater Sci Polym Ed. 2011;22 (4-6):443-56. doi: 10.1163/092050610X487738. PubMed PMID:20566039 .

2010

  • Sodha, S, Wall, K, Redenti, S, Klassen, H, Young, MJ, Tao, SL et al.. Microfabrication of a three-dimensional polycaprolactone thin-film scaffold for retinal progenitor cell encapsulation. J Biomater Sci Polym Ed. 2011;22 (4-6):443-56. doi: 10.1163/092050610X487738. PubMed PMID:20566039 .
  • Tucker, BA, Redenti, SM, Jiang, C, Swift, JS, Klassen, HJ, Smith, ME et al.. The use of progenitor cell/biodegradable MMP2-PLGA polymer constructs to enhance cellular integration and retinal repopulation. Biomaterials. 2010;31 (1):9-19. doi: 10.1016/j.biomaterials.2009.09.015. PubMed PMID:19775744 .

2009

  • Tucker, BA, Redenti, SM, Jiang, C, Swift, JS, Klassen, HJ, Smith, ME et al.. The use of progenitor cell/biodegradable MMP2-PLGA polymer constructs to enhance cellular integration and retinal repopulation. Biomaterials. 2010;31 (1):9-19. doi: 10.1016/j.biomaterials.2009.09.015. PubMed PMID:19775744 .
  • Tackenberg, MA, Tucker, BA, Swift, JS, Jiang, C, Redenti, S, Greenberg, KP et al.. Müller cell activation, proliferation and migration following laser injury. Mol. Vis. 2009;15 :1886-96. . PubMed PMID:19768129 PubMed Central PMC2746266.
  • Schmitt, S, Aftab, U, Jiang, C, Redenti, S, Klassen, H, Miljan, E et al.. Molecular characterization of human retinal progenitor cells. Invest. Ophthalmol. Vis. Sci. 2009;50 (12):5901-8. doi: 10.1167/iovs.08-3067. PubMed PMID:19553622 .
  • Redenti, S, Neeley, WL, Rompani, S, Saigal, S, Yang, J, Klassen, H et al.. Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation. Biomaterials. 2009;30 (20):3405-14. doi: 10.1016/j.biomaterials.2009.02.046. PubMed PMID:19361860 PubMed Central PMC4109162.

2008

  • Redenti, S, Tao, S, Yang, J, Gu, P, Klassen, H, Saigal, S et al.. Retinal tissue engineering using mouse retinal progenitor cells and a novel biodegradable, thin-film poly(e-caprolactone) nanowire scaffold. J Ocul Biol Dis Infor. 2008;1 (1):19-29. doi: 10.1007/s12177-008-9005-3. PubMed PMID:20072632 PubMed Central PMC2802414.
  • Neeley, WL, Redenti, S, Klassen, H, Tao, S, Desai, T, Young, MJ et al.. A microfabricated scaffold for retinal progenitor cell grafting. Biomaterials. 2008;29 (4):418-26. doi: 10.1016/j.biomaterials.2007.10.007. PubMed PMID:17961646 PubMed Central PMC2174396.

2007

  • Neeley, WL, Redenti, S, Klassen, H, Tao, S, Desai, T, Young, MJ et al.. A microfabricated scaffold for retinal progenitor cell grafting. Biomaterials. 2008;29 (4):418-26. doi: 10.1016/j.biomaterials.2007.10.007. PubMed PMID:17961646 PubMed Central PMC2174396.
  • Redenti, S, Ripps, H, Chappell, RL. Zinc release at the synaptic terminals of rod photoreceptors. Exp. Eye Res. 2007;85 (4):580-4. doi: 10.1016/j.exer.2007.07.017. PubMed PMID:17825289 .
  • Redenti, S, Chappell, RL. Müller cell zinc transporter-3 labeling suggests a role in outer retina zinc homeostasis. Mol. Med. ;13 (7-8):376-9. doi: 10.2119/2007–00041.Redenti. PubMed PMID:17622320 PubMed Central PMC1952670.
  • Tao, S, Young, C, Redenti, S, Zhang, Y, Klassen, H, Desai, T et al.. Survival, migration and differentiation of retinal progenitor cells transplanted on micro-machined poly(methyl methacrylate) scaffolds to the subretinal space. Lab Chip. 2007;7 (6):695-701. doi: 10.1039/b618583e. PubMed PMID:17538710 .

2005

2004

  • Qian, H, Chappell, RL, Redenti, S, Ripps, H. Potassium currents distinguish the two subtypes of morphologically distinct skate bipolar cells. Biol. Bull. 2004;207 (3):191-4. doi: 10.2307/1543207. PubMed PMID:15616349 .
  • Redenti, S, Chappell, RL. Localization of zinc transporter-3 (ZnT-3) in mouse retina. Vision Res. 2004;44 (28):3317-21. doi: 10.1016/j.visres.2004.07.038. PubMed PMID:15535999 .
  • Qian, H, Chappell, RL, Redenti, S, Ripps, H. Membrane Properties of Two Subtypes of Skate Bipolar Cells. Biol. Bull. 2004;207 (2):157. doi: 10.1086/BBLv207n2p157. PubMed PMID:27690577 .
  • Redenti, S, Chappell, RL. Zinc Transport in Vertebrate Retina. Biol. Bull. 2004;207 (2):158. doi: 10.1086/BBLv207n2p158. PubMed PMID:27690572 .

2003

  • Redenti, S, Chappell, RL. Zinc chelation enhances the sensitivity of the ERG b-wave in dark-adapted skate retina. Biol. Bull. 2003;205 (2):213-4. doi: 10.2307/1543258. PubMed PMID:14583535 .

2002

  • Redenti, S, Chappell, RL. Zinc chelation enhances the zebrafish retinal ERG b-wave. Biol. Bull. 2002;203 (2):200-2. doi: 10.2307/1543396. PubMed PMID:12414577 .

2001

  • Chappell, RL, Redenti, S. Endogenous zinc as a neuromodulator in vertebrate retina: evidence from the retinal slice. Biol. Bull. 2001;201 (2):265-7. doi: 10.2307/1543357. PubMed PMID:11687414 .
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